We co-develop solutions with historically excluded groups, prioritizing cultural relevance, respect, and self-determination. We recognize that digital health innovations can unintentionally reinforce inequities if they are not intentionally designed, governed, and implemented in partnership with the communities they aim to serve. We use community-centred and Indigenous-informed research approaches to understand how social, cultural, geographic, and structural factors shape access to care, technology use, trust, and health outcomes. Our projects emphasize co-design, relational engagement, and respect for Indigenous knowledge systems, values, and data governance principles. By working closely with community leaders, health workers, and policymakers, we explore how digital tools can be adapted to support culturally safe maternal, newborn, and primary health services. Our research generates evidence to inform ethical digital health design, inclusive policy, and system-level strategies that promote dignity, self-determination, and health equity for Indigenous and marginalized populations.